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IV Infusion Oncology Public Health

Clinical Trial Uses Immunotherapy to Treat Mesothelioma

Clinical Trial Uses Immunotherapy to Treat Mesothelioma

IMalignant pleural mesothelioma, an aggressive cancer that affects the lining of the lungs, is fatal in most cases. The majority of patients will die within a year and a half of diagnosis. The Mesothelioma Treatment Center at the Baylor College of Medicine Lung Institute is testing a new treatment that combines immunotherapy with a new drug that accelerates cell death. Researchers are now enrolling patients in a clinical trial.

This clinical trial treatment includes an IV infusion of a standard immunotherapy drug called Nivolumab that is effective in many human tumors and injections of a modified adenovirus called MTG201 that targets cancer cells and results in cell death. Burt has been studying the effectiveness of this combination treatment in the laboratory in animal models and said MTG201-induced cancer cell death releases tumor antigens, which allows the immunotherapy to target the cancer. The treatment also stimulated the immune system. Burt has seen remarkable results of this combination therapy in animals.

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Case Studies

I’m pleased because I don’t have to make a 4 ½-hour drive to get my infusion. It’s great that we can now have the therapy that I needed right here.


I’m very fortunate and so grateful for everything the center does for me. The wait is short and I’m in and out in no time. Without this local service, I couldn’t keep my job. I wouldn’t be able to take care of my family or enjoy my life.

CIS Rural Patient

They monitored me, they took care of me. The infection that was causing the pain began to go away. I can tell you now I’m able to stand on both legs. After the infusion therapy, I was able to resume the activity that I truly enjoy, playing the guitar and exploring the wonders of music.


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